发明名称 |
Monoclonal antibody against an acidic FGF protein and hybridoma for its production |
摘要 |
The present invention provides a hybrid cell line producing monoclonal antibody to an acidic fibroblast growth factor (aFGF) protein. The hybridoma is established by fusing spleen cells from immunized mice with myeloma cells. The hybridomas are cultured as clones, and antibodies obtained from the individual clones are tested for their specificity for aFGF protein. Antibodies can be obtained from the culture growth medium or from ascitic fluid of mice bearing the hybridoma tumor. Diagnostic and therapeutic uses of the monoclonal antibody are also disclosed.
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申请公布号 |
US5437995(A) |
申请公布日期 |
1995.08.01 |
申请号 |
US19930026257 |
申请日期 |
1993.03.04 |
申请人 |
TAKEDA CHEMICAL INDUSTRIES, LTD. |
发明人 |
ICHIMORI, YUZO;KONDO, KOICHI;IGARASHI, KOICHI;SENDO, MASAHARU |
分类号 |
C07K14/50;C07K16/22;C12N5/18;C12P21/08;(IPC1-7):C12N5/12 |
主分类号 |
C07K14/50 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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