4-Amidino chromane and 4-amidino pyrano(3,2-c)pyridine derivatives, process for preparation and pharmaceutical compositions containing them.

摘要

4-Amidinochroman and 4-amidinopyrano[3,2-c]pyridine derivatives, process for obtaining them and pharmaceutical compositions containing them. The said derivatives have antihypertensive and antiarrhythmic activities. They correspond to the formula: …… in which: … …  . A + B = -CH=CH-CH=N- or -CH=CR4-CR5=CH-; …  . X = N, N->O, C-Z; …  . R1 = H, CN, NO2, C1-C4 alkyl, OH, C1-C4 alkoxy, CF3CO-, CH3-SO2-, phi -SO2-; …  . R2 = H; …  . R3 = OH or OCOCH3 or R2 + R3 = double bond. …