摘要 |
Methods for the diagnosis of diseases that result in the release of fragments of basement membrane, including fragments, intact molecules and/or complexes of basement membrane components, are disclosed. Detection of basement membrane fragments, intact molecules and/or complexes in a biological fluid by the immunological and physicochemical methods of the present invention allows the diagnosis of a variety of diseases, including cancers, collagen degenerative diseases, and hepatitis. Suitable biological fluids include urine, serum, synovial fluid, and cerebrospinal fluid. |