发明名称 COMPOSITION FOR INTRODUCING NUCLEIC ACID COMPLEXES INTO EUCARYOTIC CELLS, COMPLEX CONTAINING NUCLEIC ACID AND ENDOSOMOLYTIC AGENT, PEPTIDE WITH ENDOSOMOLYTIC DOMAIN AND NUCLEIC ACID BINDING DOMAIN AND PREPARATION
摘要 Composition for the transfection of higher eukaryotic cells with a complex of nucleic acid and substance which has affinity for nucleic acids and is optionally conjugated with an internalisation factor for these cells. The composition contains an endosomolytic agent which is either a free or a bound virus or a virus component or a viral or non-viral peptide with endosomolytic properties. <IMAGE>
申请公布号 NZ244306(A) 申请公布日期 1995.07.26
申请号 NZ19920244306 申请日期 1992.09.11
申请人 BOEHRINGER INGELHEIM INTERNATIONAL GMBH;THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL 发明人 CURIEL, DAVID T;WAGNER, ERNST;BIRNSTIEL, MAX L;COTTEN, MATTHEW;ZATLOUKAL, KURT;PLANK, CHRISTIAN
分类号 C12N15/09;A61K35/76;A61K38/00;A61K38/21;A61K38/36;A61K39/44;A61K47/48;A61K48/00;A61P31/12;A61P35/00;C07K14/005;C07K14/075;C07K14/095;C07K14/11;C07K14/15;C07K14/16;C07K14/56;C07K14/775;C07K14/79;C07K16/00;C07K16/28;C12N5/10;C12N7/04;C12N15/34;C12N15/41;C12N15/44;C12N15/87;(IPC1-7):C12N15/34;C12N7/00;C12P21/00;C07K15/06;C12P21/02 主分类号 C12N15/09
代理机构 代理人
主权项
地址