发明名称 |
BENZIMIDAZOLYL OR XANTHYL SUBSTITUTED PIPERDINE OR PIPERAZINE DERIVATIVES AND MEDICAMENTS |
摘要 |
PCT No. PCT/FR91/00811 Sec. 371 Date Feb. 8, 1993 Sec. 102(e) Date Feb. 8, 1993 PCT Filed Oct. 17, 1991 PCT Pub. No. WO92/06977 PCT Pub. Date Apr. 30, 1992. <IMAGE> (I) The present invention concerns (4-substituted phenyl)4-oxy 1-aminobutane of the general formula (I) in which X is a nitrogen atom or >CH-CH, and R is a cyclic substituent chosen from the group comprising a) a xanthic substituent, b) a benzimidazolic substituent, as well as salts and optic isomers of the compounds of formula (I). The invention also concerns processes for obtaining the compounds of formula (I) and pharmaceutical compositions containing, as antihistamine ingredient, at least one compound of formula (I) or one of its salts with a mineral or organic acid. |
申请公布号 |
NZ240274(A) |
申请公布日期 |
1995.07.26 |
申请号 |
NZ19910240274 |
申请日期 |
1991.10.17 |
申请人 |
LABORATOIRE THERAMEX SA |
发明人 |
BONNET, PAULE;DELANSORNE, REMI;FAURE, MAURICE;LANQUETIN, MICHEL;ZUNINO, SERGE |
分类号 |
A61K31/415;A61K31/4184;A61K31/4427;A61K31/4433;A61K31/445;A61K31/4468;A61K31/454;A61K31/495;A61K31/496;A61K31/52;A61K31/522;A61P11/14;A61P37/08;A61P43/00;C07D;C07D211/46;C07D235/30;C07D295/08;C07D401/12;C07D403/12;C07D409/04;C07D473/08 |
主分类号 |
A61K31/415 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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