发明名称 |
Aminoanthraquinone derivatives to combat multidrug resistance |
摘要 |
Potentiating agents inhibit the development of multidrug resistance, reduce drug-resistance in drug-resistant tumors, or sensitize tumors to antineoplastic drugs, thereby potentiating the effect of antineoplastic agents. The potentiating agents are aminoanthraquinones, preferably 1,4-bis(N-substituted) amino anthraquinones, and pharmaceutically acceptable salts thereof.
|
申请公布号 |
US5436243(A) |
申请公布日期 |
1995.07.25 |
申请号 |
US19930152894 |
申请日期 |
1993.11.17 |
申请人 |
RESEARCH TRIANGLE INSTITUTE DUKE UNIVERSITY;PHARMACEUTICALS CORPORATION |
发明人 |
SACHS, CLIFFORD W.;FINE, ROBERT L.;BALLAS, LAWRENCE M;CARROLL, R. IVY;BELL, ROBERT |
分类号 |
A61K31/445;A61K31/475;A61K31/495;A61K31/535;A61K45/06;(IPC1-7):A61K31/135;A61K31/55 |
主分类号 |
A61K31/445 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|