发明名称 |
Chemotactic wound healing peptides |
摘要 |
Peptides corresponding to an no acid sequences in the C-terminal region of TGF- beta are provided. The peptides all contain at least a seven amino acid sequence substantially corresponding to the amino acid sequence of TGF- beta 1 amino acids 368-374: VYYVGRK, as well as homologs and analogs thereof. The peptides have chemotactic activity towards fibroblasts, monocytes and neutrophils and induce fibroblast proliferation and collagen synthesis. The peptides may be used in compositions and methods for promoting wound healing.
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申请公布号 |
US5436228(A) |
申请公布日期 |
1995.07.25 |
申请号 |
US19930127909 |
申请日期 |
1993.09.28 |
申请人 |
POSTLETHWAITE, ARNOLD E.;SEYER, JEROME;KANG, ANDREW |
发明人 |
POSTLETHWAITE, ARNOLD E.;SEYER, JEROME;KANG, ANDREW |
分类号 |
A61K38/00;C07K14/495;(IPC1-7):A61K38/00;C07K5/00;C07K7/00;C07K17/00 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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