发明名称 |
BENZENESULFONAMIDE DERIVATIVE AND USE THEREOF. |
摘要 |
<p>A benzenesulfonamide derivative represented by general formula (I) and a pharmacologically acceptable salt thereof, wherein R<1> represents hydrogen, lower alkyl, lower alkoxy or halogen; R<2> represents C1-C10 linear or branched alkyl, C3-C8 cycloalkyl optionally substituted by C1-C6 alkyl, C1-C6 alkyl substituted by C3-C8 cycloalkyl, 1-adamantylmethyl, 2-norbornylmethyl or phenyl-substituted C1-C6 alkyl which may be substituted on the benzene ring; R<3> represents hydrogen or lower alkyl; and n represents an integer of 2 to 4. The compound has a thromboxane A2 antagonism, a leucotriene antagonism, and so on, thus being useful as platelet aggregation inhibitor, antithrombotic, antiasthmatic, and antiallergic.</p> |
申请公布号 |
EP0663392(A1) |
申请公布日期 |
1995.07.19 |
申请号 |
EP19930921078 |
申请日期 |
1993.09.29 |
申请人 |
HOKURIKU SEIYAKU CO., LTD. |
发明人 |
ITO, YASUO 11-14, MOTO-MACHI 3-CHOME;KATO, HIDEO 5-8, KENTOKU 3-CHOME;YASUDA, SHINGO 6-5, ASAHI-CHO 2-CHOME;OGAWA, NOBUO 6-5, ASAHI-CHO 2-CHOME;SAKURAI, SHUNICHIRO 12-6-2, INOKEYA;SUZUKI, TOMIO 19-15, OHTSUKI |
分类号 |
C07C311/19;C07C311/29;(IPC1-7):C07C311/19;A61K31/18 |
主分类号 |
C07C311/19 |
代理机构 |
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代理人 |
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地址 |
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