PROCESS FOR THE PREPARATION OF ANTI-INFLAMMATORY PHARMACEUTICAL AGENTS WITH AN IBUPROFEN BASE, WITH ELIMINATION, IN SOLUTION, OF THE BITTER TASTE, BURNING OF THE THROAT AND INTESTINAL TOXICITY

摘要

Disclosed in an anti-inflammatory pharmaceutical composition comprising the following ingredients in intimate admixture: ibuprofen, 200 to 800 mg or ibuprofen sodium salt, 221.2 to 885.2 mg; sodium bicarbonate, 2.100 to 8.402 g; and citric acid, 0.450 to 1.800 g. This composition which can be in the form of an effervescent solution or a tablet, permits to eliminate the bitter taste, the burning of the throat and the topical toxicity at the level of the intestinal wall, that are otherwise encountered with similar compositions.