Nootropic agents, compositions of, and method of use thereof

摘要

An aromatic amino-substituted compound represented by formula: <IMAGE> (I) wherein A represents CH, N, or N->O; R1 represents a nitro group or an amino group; R2 represents a hydrogen atom, a lower alkyl group, or an acyl group; and R3 represents a group: <IMAGE> wherein m represents 0 or 1; n represents an integer of from 0 to 3; R4 and R5 each represents a hydrogen atom or a lower alkyl group; R6 and R7 each represents a hydrogen atom or a straight chain or branched lower alkyl group; R4 and R6 may be joined together to form an alkylene chain forming a heterocyclic ring; R5 and R7 may be joined together to form an alkylene chain forming a heterocyclic ring and R6 and R7 may be joined together to form an alkylene chain forming a heterocyclic ring, or a pharmaceutically acceptable salt thereof, a process for producing the same, and a method for preventing or treating brain disfunction such as senile dementia or Alzheimer's disease by administering a nootropic agent containing the same as an active ingredient are disclosed.