| 摘要 |
Disclosed are beta -carboline derivatives represented by the formula: <IMAGE> wherein R1 represents hydrogen atom, a lower alkyl group, a lower alkoxy group or hydroxy group; R5 represents hydrogen atom, or R1 and R5 are bonded to represent a lower alkylenedioxy group; R2 represents hydrogen atom, a halogen atom, a lower alkoxy group or hydroxy group; R3 represents hydrogen atom, a carbamoyl lower alkyl group, a lower alkyl group, a carboxy lower alkyl group or a lower alkoxycarbonyl lower alkyl group; R4 represents hydrogen atom, a lower alkyl group, a carboxy lower alkyl group, a lower alkoxycarbonyl lower alkyl group, a lower alkanoyl group, an arylcarbonyl group, a lower alkanesulfonyl group, a lower alkoxycarbonyl group, an aralkyl group, formyl group or a di(lower alkyl)sulfamoyl group; n represents 0, 1 or 2; and the symbol * represents an asymmetric carbon atom, or a pharmaceutically acceptable salt thereof, and a process for preparing the same.
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