Sulfonamide derivatives

摘要

Sulfonamide derivatives of the general formula (I): <IMAGE> (I) wherein preferably R1 represents a lower alkoxy group, R2, R3, R4, R5, R6 and R7 may be the same or different from one another and each represent a hydrogen atom, halogen atom or lower alkyl group, A and B may be the same or different from each other and each represent =N- or =CH-, E represents an aromatic 6-membered cyclic group, which may have 1 or 2 nitrogen atoms in the ring, and be substituted with 1 to 3 substituents which may be the same or different from one another with the proviso that a combination of R1 which is a hydrogen atom, lower alkyl group, nitro group or amino group which may be protected, R2 and R3 which are each a hydrogen atom, A and B which are each =CH- and E which is a phenyl group which may be substituted with 1 to 3 substituents G which may be the same or different from one another is excluded, or pharmacologically acceptance salts of them, have an excellent antitumo-activity.