发明名称 |
Asymmetric hydrogenation of furoimidazole derivatives |
摘要 |
A process for the asymmetric hydrogenation of furoimidazole derivatives of the general formula: <IMAGE> I with hydrogen in the presence of a homogeneous catalyst to give the corresponding diastereomeric dihydrofuroimidazole derivatives of the general formula: <IMAGE> II R1 and R2 are protective groups, although R2 can be hydrogen. The dihydrofuroimidazole derivatives of the general formula II are intermediates for the preparation of (+)-biotin.
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申请公布号 |
US5434269(A) |
申请公布日期 |
1995.07.18 |
申请号 |
US19940285759 |
申请日期 |
1994.08.03 |
申请人 |
LONZA LTD. |
发明人 |
EYER, MARTIN;MERRILL, RONALD E. |
分类号 |
B01J31/24;C07D491/04;C07D491/048;C07F17/02;C07F19/00;(IPC1-7):C07D491/048;C07D491/044 |
主分类号 |
B01J31/24 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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