<p>Sterile pharmaceutical compositions for use in therapy especially inactivated vaccines for use in prophylaxis, are prepared by inactivating a live virus or bacterium with ascorbic acid and/or a salt thereof in the presence of oxygen and a source of heavy metal ions. Methods of treating animals, including humans, with such compositions are also disclosed.</p>
申请公布号
DE3852918(T2)
申请公布日期
1995.07.13
申请号
DE19883852918T
申请日期
1988.09.26
申请人
BEECHAM INC., PHILADELPHIA, PA., US
发明人
BORDT, DALE, C/O BEECHAM LABORATORIES, WHITE HALL, IL 62092, US;DRAAYER, HANS BEECHAM INC., BEECHAM LABORATORIES, ILLINOIS, 62092, US