A new Factor VIII derivative comprising a functional A2 domain, in which one or more cysteine residues have been deleted or substituted by one or more other amino acid residues, said Factor VIII derivative shows a coagulant activity of Factor VIII which is stable for an extended period.
申请公布号
WO9518827(A1)
申请公布日期
1995.07.13
申请号
WO1995DK00008
申请日期
1995.01.06
申请人
NOVO NORDISK A/S;NICOLAISEN, ELSE, MARIE;PERSSON, EGON;EZBAN RASMUSSEN, MIRELLA
