发明名称 METHOD OF IDENTIFYING CHEMICAL COMPOUNDS HAVING SELECTED PROPERTIES FOR A PARTICULAR APPLICATION
摘要 A method for obtaining compounds having selected properties for a particular application by forming base modules having at least two structural diversity elements from the reaction of a first compound having at least one structural diversity element and a first reactive group, with a second compound having at least one structural diversity element and a second reactive group, wherein the first and second groups combine by an addition reaction; producing a first array of molecules by varying at least one of the structural diversity elements of the compounds when producing the base modules; and screening the array to determine a first suitable compound for the particular application. The base modules are preferably formed from oxazolone- and aminimide-derived compounds. If desired, the method can be repeated by producing a second array of molecules through the formation of base modules having structural diversity elements that are modified from those of the first suitable compound; and screening the second array of molecules to determine a second suitable compound for the particular application. The second array producing and screening steps can be repeated as often as necessary to achieve an optimum compound for the particular application.
申请公布号 CA2180526(A1) 申请公布日期 1995.07.13
申请号 CA19942180526 申请日期 1994.01.05
申请人 ARQULE, INC. 发明人 HOGAN, JOSEPH C., JR.
分类号 G01N33/48;C07B61/00;C07C243/40;C07D263/42;C07D265/10;C07D267/06;C07D295/32;C07D307/54;C07D333/24;C07D405/12;C07D409/12;C07D413/12;C07K5/00;C07K7/00;C07K14/00;G01N33/53;G01N33/566;(IPC1-7):C07K5/00 主分类号 G01N33/48
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