发明名称 |
Bisulfite-based tissue fixative |
摘要 |
The present invention provides a bisulfite-based tissue fixative that improves morphology, antigen retention, and antigenicity. The fixative is suitable for use with sections of frozen tissue, cytology preparations (including touch preparations and blood smears) and other specimens used for immunohistochemical analysis. The fixative comprises an acidic buffer and a bisulfite salt in an effective amount for tissue fixation. In a preferred embodiment, the tissue fixative comprises a bisulfite salt in a concentration of from about 0.01 to about 0.25M, preferably, 0.02 to 0.25M, in an acidic buffer having a pH of from about 2 to about 6.
|
申请公布号 |
US5432056(A) |
申请公布日期 |
1995.07.11 |
申请号 |
US19930152863 |
申请日期 |
1993.11.15 |
申请人 |
VENTANA MEDICAL SYSTEMS, INC. |
发明人 |
HARTMAN, ANTHONY L.;KLOTZ, JANIS L.;JONES, CHRISTINE R. |
分类号 |
G01N1/30;(IPC1-7):G01N33/543 |
主分类号 |
G01N1/30 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|