发明名称 Haemorheological use of N-alkylated 1,4-dihydropyridine-dicarboxylic acid esters, and some new compounds
摘要 Improving circulation, with minimal effect on blood pressure, using N-alkylated 1,4-dihydropyridines of the formula <IMAGE> (I) in which R1 represents hydrogen, nitro, cyano, trifluoromethyl, trifluoromethoxy, halogen or methyl, R2 represents hydrogen, halogen, nitro, hydroxyl, trifluoromethyl or methyl, R3 represents hydrogen or cyano, or R2 and R3 together form a fused benzo ring, R4 and R5 are identical or different and represent straight-chain or branched alkyl having up to 8 carbon atoms, which is optionally substituted by alkoxy having up to 4 carbon atoms, and R6 represents straight-chain or branched alkyl having up to 10 carbon atoms or represents cycloalkyl having 3 to 7 carbon atoms. Many of the compounds are new.
申请公布号 US5432185(A) 申请公布日期 1995.07.11
申请号 US19930065503 申请日期 1993.05.21
申请人 BAYER AKTIENGESELLSCHAFT 发明人 BEHNER, OTTO;WOLLWEBER, HARTMUT;ROSEN, BRUNO;ZAISS, SIEGFRIED;GOLDMANN, SIEGFRIED
分类号 A61K31/445;A61K31/44;A61K31/451;A61P9/08;A61P9/10;C07D211/90;(IPC1-7):A61K31/455 主分类号 A61K31/445
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