发明名称 |
Macrophage inflammatory proteins-3, -4 and -1Õsg(g)? |
摘要 |
There are disclosed a human macrophage inflammatory protein-3, a human macrophage inflammatory protein-4 and a human macrophage inflammatory protein-1 gamma polypeptides and DNA (RNA) encoding such polypeptides. There is also provided a procedure for producing such polypeptides by recombinant techniques and for producing antibodies against such polypeptides. In the invention there is also provided antagonist/inhibitors against such polypeptides which inhibit the functioning of such polypeptides. Another aspect of the invention provides a combination of the polypeptides of the present invention and a suitable pharmaceutical carrier for providing a therapeutically effective amount of the polypeptides for the treatment of various associated diseases. |
申请公布号 |
AU7549794(A) |
申请公布日期 |
1995.07.10 |
申请号 |
AU19940075497 |
申请日期 |
1994.06.28 |
申请人 |
HUMAN GENOME SCIENCES, INC. |
发明人 |
HAODONG LI;CRAIG A ROSEN;STEVE RUBEN;MARK D ADAMS |
分类号 |
C12N15/09;A01N37/18;A61K38/00;A61K48/00;A61P7/00;A61P9/10;A61P11/10;A61P17/00;A61P17/06;A61P29/00;A61P31/00;A61P35/00;A61P35/02;A61P37/00;A61P37/08;A61P43/00;C07H21/04;C07K14/47;C07K14/52;C07K16/18;C07K16/24;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12P21/02;C12Q1/02;C12R1/19;C12R1/91 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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