摘要 |
The present invention is directed towards climinating disadvantages of a prefilled syringe (1, 11, 15, 20, 25, 35, 40, 45, 50, 55, 100) including removal of a piston (6, 107) and leakage of a loaded liquid without disturbing the movement of the piston. A prefilled syringe according to the present invention having an outer cylinder (2, 105) which has a nozzle (4) provided in one end thereof and an opening (3, 103) provided in the other end thereof and accommodates therein a piston (6, 107) inserted from the other end, is characterized by a retainer (9, 13) disposed on the other end side of the piston in the outer cylinder (2, 105) for providing a tightness to an inner wall of the outer cylinder. Also, a tooling for preventing removal of the piston according to the present invention is provided comprising a spacer (71) for mounting on the other end side of the piston in the outer cylinder, an other end side retainer plate (72) attached to an other end side of the flange (104) for preventing removal of the piston from the outer cylinder, a one-end side retainer plate (73) attached to a one end side of the flange, and a tightening member (74) for sandwiching and tightening the flange of the prefilled syringe between the other end side retainer plate and the one end side retainer plate. |
申请人 |
EISAI CO., LTD.;WATANABE, TAKESHI;IKEUCHI, TAKAYUKI;WATANABE, SUMIO |
发明人 |
WATANABE, TAKESHI;IKEUCHI, TAKAYUKI;WATANABE, SUMIO |