USE OF 2-MERCAPTO-IMIDAZOLE DERIVATIVES SUBSTITUTED IN POSITION 4 (OR 5) AS ANTIOXIDIZING AGENTS, METHOD OF PREPARATION AND APPLICATIONS IN THE PHARMACEUTICAL, COSMETIC OR FOOD INDUSTRIES

摘要

2-mercapto-imidazole derivatives substituted in position 4 (or 5) of general formula (I), wherein R1, R2, R5, R6, R7, R8 are hydrogen, lower alkyl, aralkyl or substituted aralkyl; at least R1 or R2 being hydrogen; R3 is -(CH2)nCOR4; -(CH2)nN<+>(R5R6R7),X<->; -CH2CH(COR4)N<+>-(R5R6R7),X<->; R4 is -OR8; -NHR5; - alpha -amino acid, preferably a natural- alpha -amino acid; -NHCH2CH2SO3<->,Y<+>; -NHCH2CH2CO2<->,Y<+>; -OCH2CH2N<+>(CH3)3,X<->; (a), <->, (b), (c), n = 1 or 2, X<-> is an anion of an acid acceptable in the cosmetic, pharmaceutical or food industries. Y<+> is a cation of a base acceptable in the cosmetic, pharmaceutical or food industries. Said compounds are useful as antioxidizing agents and as active ingredients of a composition having an antioxydizing activity useful in the pharmaceutical, cosmetic or food industries.