| 发明名称 |
IMPROVED PROCESS FOR THE PURIFICATION OF OLIGOMERS |
| 摘要 |
Methods for purifying an oligomer by normal phase column chromatography on a support selected from polyhydroxyethyl aspartamide, hydrophilic silica and silica from an oligomer impurity having a different nucleoside sequence are described. These methods are based upon the different retention times of the oligomer and the impurity on the column.
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| 申请公布号 |
WO9518137(A1) |
申请公布日期 |
1995.07.06 |
| 申请号 |
WO1994US14898 |
申请日期 |
1994.12.30 |
| 申请人 |
GENTA INCORPORATED |
发明人 |
RILEY, TIMOTHY, ANDREW;REYNOLDS, MARK, ALAN;SNYDER, LLOYD, ROBERT;KLEM, ROBERT, E. |
| 分类号 |
B01D15/08;C12N15/10;(IPC1-7):C07H1/06;C07H21/00;C07H21/02;C07H21/04;C08K3/36;C08K3/34;C08L5/16 |
主分类号 |
B01D15/08 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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