METHODS AND COMPOSITIONS FOR THE TREATMENT OF A HOST WITH A CELLULAR PROLIFERATIVE DISEASE

摘要

Methods and compositions are provided for the treatment of a hostwith a cellular proliferative disease, particularly a neoplasia. In the subject methods, a pharmaceutically acceptable, substantially anhydrous, injectable semi-solid composition which acts as a depot for a cytostatic agent, is administered to a lesion of the disease, particularly intralesionally. The subject compositions comprise a water immiscible, fatty acid ester matrix and a cytostatic agent.