发明名称 |
Orally active renin inhibitors. |
摘要 |
<p>This invention relates to compounds of the formula <CHEM> wherein Z, D, E, R<3>, R<4>, R<5> and R<6> are specified substituents and Q is of the formula: <CHEM> where Y is CH or N, l is O or 1 and R<1> and R<2> are specified substituents. The compounds are useful as antihypertensive agents.</p> |
申请公布号 |
EP0661292(A1) |
申请公布日期 |
1995.07.05 |
申请号 |
EP19950200133 |
申请日期 |
1991.01.11 |
申请人 |
PFIZER INC. |
发明人 |
HOOVER, DENNIS J.;LEFKER, BRUCE A.;ROSATI, ROBERT L. |
分类号 |
A61K38/00;A61K31/16;A61K31/445;A61K31/4465;A61K31/4468;A61P9/00;A61P9/12;A61P27/02;C07C59/205;C07C237/22;C07D205/04;C07D211/26;C07D211/58;C07D211/74;C07D333/24;C07D401/12;C07D405/12;C07D471/04;C07D409/06;C07D409/12;C07D417/12;C07K5/02;C07K5/023;C07K5/06;C07K5/065;C07K5/078;C07K14/81;(IPC1-7):C07K5/023;C07D211/56;C07D339/02;C07D339/08;C07D317/12;C07D211/46;C07D277/28;C07D277/64;A61K38/05;C07D319/06 |
主分类号 |
A61K38/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|