发明名称 Orally active renin inhibitors.
摘要 <p>This invention relates to compounds of the formula &lt;CHEM&gt; wherein Z, D, E, R&lt;3&gt;, R&lt;4&gt;, R&lt;5&gt; and R&lt;6&gt; are specified substituents and Q is of the formula: &lt;CHEM&gt; where Y is CH or N, l is O or 1 and R&lt;1&gt; and R&lt;2&gt; are specified substituents. The compounds are useful as antihypertensive agents.</p>
申请公布号 EP0661292(A1) 申请公布日期 1995.07.05
申请号 EP19950200133 申请日期 1991.01.11
申请人 PFIZER INC. 发明人 HOOVER, DENNIS J.;LEFKER, BRUCE A.;ROSATI, ROBERT L.
分类号 A61K38/00;A61K31/16;A61K31/445;A61K31/4465;A61K31/4468;A61P9/00;A61P9/12;A61P27/02;C07C59/205;C07C237/22;C07D205/04;C07D211/26;C07D211/58;C07D211/74;C07D333/24;C07D401/12;C07D405/12;C07D471/04;C07D409/06;C07D409/12;C07D417/12;C07K5/02;C07K5/023;C07K5/06;C07K5/065;C07K5/078;C07K14/81;(IPC1-7):C07K5/023;C07D211/56;C07D339/02;C07D339/08;C07D317/12;C07D211/46;C07D277/28;C07D277/64;A61K38/05;C07D319/06 主分类号 A61K38/00
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