| 发明名称 |
CYTOKERATIN TUMOR MARKERS AND ASSAYS FOR THEIR DETECTION |
| 摘要 |
Methods and compositions are provided for identifying patients suffering from neoplastic diseases such as breast cancer. It has been found that neoplastic epithelial cells, including neoplastic mammary epithelial cells, release a particular N-terminal blocked, soluble cytokeratin into circulation. The presence of this cytokeratin is diagnostic of neoplastic disease. Hybridoma cell line UCD/AB 611 was deposited at the American Type Culture collection on December 8, 1983 and granted accession no. HB 8458. Hybridoma cell line UCD/PR 10.11 was deposited at the American Type Culture Collection on January 3, 1985, and granted accession no. HB 8694.
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| 申请公布号 |
CA1336171(C) |
申请公布日期 |
1995.07.04 |
| 申请号 |
CA19850471619 |
申请日期 |
1985.01.07 |
| 申请人 |
REGENTS OF THE UNIVERSITY OF CALIFORNIA (THE) |
发明人 |
CARDIFF, ROBERT D.;ROSSITTO, PAUL V.;BRABON, ALAN C. |
| 分类号 |
C07K14/195;A61K39/00;A61K39/395;C07K14/005;C07K14/705;C07K14/78;C07K16/00;C07K16/18;C07K16/28;C07K16/30;C07K16/32;C12N5/00;C12N5/10;C12N15/00;C12N15/02;C12N15/09;C12P21/00;C12P21/08;C12Q1/00;C12R1/91;G01N33/574;G01N33/577;(IPC1-7):C12P21/08;C07K15/06;C12N5/18;C07K15/20 |
主分类号 |
C07K14/195 |
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