发明名称 |
Cyclische Derivate des Amidinylthiocarbapenems. |
摘要 |
<p>A compound represented by formula (I): <CHEM> wherein R<1> represents a hydrogen atom or a methyl group; R<2> and R<3>, which may be the same or different, each represents a hydrogen atom or a lower alkyl group; and R<4> represents a carboxyl group, a lower alkoxycarbonyl group, a carbamoyl group, a lower alkylcarbamoyl group, a di-lower alkylcarbamoyl group, or a carbonyl group substituted with a heterocyclic group selected from the group consisting of an aziridinyl group, an azetidinyl group, a pyrrolidinyl group, a piperidino group, a morpholino group, a thio-morpholino group, a piperazinyl group, and a 4-lower alkyl-1-piperazinyl group, or a pharmaceutically acceptable salt or ester thereof. The compound of formula (I) and their salts or esters exhibit excellent antibacterial activity.</p> |
申请公布号 |
DE69019610(D1) |
申请公布日期 |
1995.06.29 |
申请号 |
DE1990619610 |
申请日期 |
1990.07.05 |
申请人 |
BANYU PHARMACEUTICAL CO., LTD., TOKIO/TOKYO, JP |
发明人 |
NAKAGAWA, SUSUMU, C/O BANYU PHARMACEUTICAL CO. LTD, OKAZAKI-SHI, AICHI, JP;KATO, YOSHIAKI, C/O BANYU PHARMACEUTICAL CO. LTD, OKAZAKI-SHI, AICHI, JP;FUKATSU, HIROSHI, C/O BANYU PHARMACEUTICAL CO. LTD, OKAZAKI-SHI, AICHI, JP |
分类号 |
C07D477/00;A61K31/397;A61K31/40;A61P31/04;C07D207/24;C07D477/20;(IPC1-7):C07D477/00;C07D207/22 |
主分类号 |
C07D477/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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