发明名称 |
PARATHYROID HORMONE FORMULATION |
摘要 |
Described herein are preparations containing parathyroid hormone that has been stabilized with an excipient and buffering agent. Preferred preparations incorporate human PTH(1-84), mannitol as excipient and citrate as buffering agent, and are incorporated in vials as a freeze-dried powder for reconstitution to treat osteoporosis.
|
申请公布号 |
WO9517207(A1) |
申请公布日期 |
1995.06.29 |
申请号 |
WO1994CA00693 |
申请日期 |
1994.12.16 |
申请人 |
ALLELIX BIOPHARMACEUTICALS INC.;GLAXO CANADA INC. |
发明人 |
HOLTHUIS, JOSEPHUS, JOHANNES, MARIA;MEKKING, ALBERT;VOETMAN, ALWINUS, ANTONIUS |
分类号 |
A61K9/14;A61K9/00;A61K9/19;A61K38/22;A61K38/29;A61K47/10;A61K47/12;A61K47/26;A61P3/02;A61P3/14;A61P19/10;A61P43/00;(IPC1-7):A61K38/29 |
主分类号 |
A61K9/14 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|