摘要 |
<p>A method and device are provided for determining the genotype at selected loci within genetic material obtained from a biological sample. One or more data sets are formed and probability distributions established. These distributions associate hypothetical reaction values with corresponding probabilities for each genotype of interest at the same locus or at different loci. The genotype is then determined based on these measures. The foregoing methods have been employed for automatic genotype determination based on assays using genetic bit analysis. The methods of the invention have been embodied in a device suitable for determining the genotype at selected loci within genetic material obtained from the subject.</p> |