New fused di:hydro-pyridine derivs.

摘要

Fused dihydropyridine derivs. of formula (I) and their acid-addn. salts and complexes are new: A = benzo substd. by 2 or 3 of OH, 1-4C alkoxy, benzyloxy, halo, 1-4C alkyl, OSO2Me and NHSO2Me, or by methylenedioxy or ethylenedioxy; or unsubstd. indolo or thieno; R1 = CR7R8R9; R7-R9 = Me, Et, Pr,etc.;R3,R4 = H; 3-6C alkenyl or alkynyl; or 1-12C alkyl opt. substd. by OH, 1-4C alkoxy,etc. or Ar; or R3 = H and R4 = cyclohexyl, Ar, pyridyl or N-benzylpiperidyl; or NR3R4 = pyrrolidino, piperidino, morpholino, thiomorpholino or 4-Q-1-piperazinyl; Ar = phenyl substd. by 0-3 of OH, 1-4C alkoxy, benzyloxy, halo, CF3,etc.;Q = H, Me, Ph, mono- or di(1-4C alkoxy)phenyl,etc..