发明名称 Zusammensetzung zur verlängerter Freigabe und Polymere dafür.
摘要 1. A polymer for a prolonged release preparation which comprises (A) a polylactic acid and (B) a copolymer of glycolic acid and a hydroxycarboxylic acid of general formula <CHEM> wherein R stands for an alkyl group having 2 to 8 carbons, and wherein the weight ratio of (A) and (B) is in the range of 10/90 to 90/10. The drug is released at a constant rate from the preparation over the total release period without a large burst at the initial stage. Furthermore, the drug release period of the preparation can be freely controlled by varying the blending ratio of (A) and (B).
申请公布号 DE69107773(T2) 申请公布日期 1995.06.29
申请号 DE1991607773 申请日期 1991.10.15
申请人 TAKEDA CHEMICAL INDUSTRIES, LTD., OSAKA, JP 发明人 YAMADA, MINORU, KAWANISHI, HYOGO 666-01, JP;ISHIGURO, SEIKO, KAWANISHI, HYOGO 666-01, JP;OGAWA, YASUAKI, OHYAMAZAKI-CHO, OTOKUNI-GUN, KYOTO 618, JP
分类号 A61K9/14;A61K9/16;A61K9/22;A61K9/50;A61K9/52;A61K38/00;A61K45/00;A61K47/34;C08G63/08;C08L67/00;C08L67/04 主分类号 A61K9/14
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