发明名称 USE OF PLA2 INHIBITORS AS TREATMENT FOR ALZHEIMER'S DISEASE
摘要 This invention provides methods for the treatment or prevention of Alzheimer's disease in a mammal which comprises administering to a mammal in need thereof an effective amount of an inhibitor of phospholipase A2. This invention also provides a series of compounds which are useful as inhibitors of phospholipases A2, especially cytosolic phospholipase A2.
申请公布号 WO9517183(A1) 申请公布日期 1995.06.29
申请号 WO1994US14504 申请日期 1994.12.14
申请人 ELI LILLY AND COMPANY 发明人 CLEMENS, JAMES, ALLEN;SOFIA, MICHAEL, JOSEPH;STEPENSON, DIANE, TERESA
分类号 C07D311/66;A61K31/00;A61K31/165;A61K31/18;A61K31/19;A61K31/35;A61K31/352;A61K31/41;A61K45/00;A61P25/28;A61P43/00;C07C59/68;C07C65/21;C07C65/32;C07C65/40;C07C69/712;C07C235/34;C07C311/51;C07D257/04;C07D311/86;(IPC1-7):A61K31/41;A61K31/355 主分类号 C07D311/66
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