发明名称 |
USE OF PLA2 INHIBITORS AS TREATMENT FOR ALZHEIMER'S DISEASE |
摘要 |
This invention provides methods for the treatment or prevention of Alzheimer's disease in a mammal which comprises administering to a mammal in need thereof an effective amount of an inhibitor of phospholipase A2. This invention also provides a series of compounds which are useful as inhibitors of phospholipases A2, especially cytosolic phospholipase A2.
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申请公布号 |
WO9517183(A1) |
申请公布日期 |
1995.06.29 |
申请号 |
WO1994US14504 |
申请日期 |
1994.12.14 |
申请人 |
ELI LILLY AND COMPANY |
发明人 |
CLEMENS, JAMES, ALLEN;SOFIA, MICHAEL, JOSEPH;STEPENSON, DIANE, TERESA |
分类号 |
C07D311/66;A61K31/00;A61K31/165;A61K31/18;A61K31/19;A61K31/35;A61K31/352;A61K31/41;A61K45/00;A61P25/28;A61P43/00;C07C59/68;C07C65/21;C07C65/32;C07C65/40;C07C69/712;C07C235/34;C07C311/51;C07D257/04;C07D311/86;(IPC1-7):A61K31/41;A61K31/355 |
主分类号 |
C07D311/66 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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