Novel imidazole derivative and process for producing the same

摘要

The invention relates to the imidazole derivatives as selective antagonistic substances against muscarinic acetylcholine and provides imidazole derivatives represented by a general formula (1) or (2) Äwherein R1 is a phenyl group which may have substituent or thienyl group, R2 is a cyano group, a carboxy group, CONR7R8 group (wherein R7 and R8 each independently represent hydrogen atom or lower alkyl group, or R7and R8 may form a ring by alkylene chain which may contain hetero atom) or COOR9 group (wherein R9 is a lower alkyl group), R3 is a hydrogen atom or lower alkyl group, R4, R5 and R6 each independently represent hydrogen atom, lower alkyl group which may have substituent or cycloalkyl groups, or may form a condensed ring at the positions of R5 and R6 with benzene ring, R10 is a lower alkyl group or aralkyl group which may have substituent, m is an integer from 1 to 6, and Z is a halogen atomÜ.