发明名称 |
Dopamine receptor ligands and imaging agents |
摘要 |
Novel CNS dopamine D-2 receptors, such as the compound 5-iodo-7-N-[(1-ethyl-2-pyrrolidinyl)methyl]carboxamide-2,3-dihydrobenzofuran, are disclosed. These compounds are useful as imaging agents for D-2 receptors in the human brain and exhibit good brain retention and in vivo stability.
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申请公布号 |
US5426189(A) |
申请公布日期 |
1995.06.20 |
申请号 |
US19940248313 |
申请日期 |
1994.05.24 |
申请人 |
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA |
发明人 |
KUNG, HANK F.;MURPHY, RAYMOND |
分类号 |
A61K51/00;A61K51/04;C07D207/09;C07D405/12;(IPC1-7):C07F7/22;C07F7/10;C07F3/14;C07D403/12 |
主分类号 |
A61K51/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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