| 发明名称 |
Pyrimidinyl-glutamic acid derivatives |
| 摘要 |
The present invention provides novel pyrimidinyl-glutamic acid derivatives and intermediates thereto. Further provided are methods for inhibiting dihydrofolate reductase in mammals and for treating susceptible neoplasms in mammals, particularly humans.
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| 申请公布号 |
US5426110(A) |
申请公布日期 |
1995.06.20 |
| 申请号 |
US19930132514 |
申请日期 |
1993.10.06 |
| 申请人 |
ELI LILLY AND COMPANY |
发明人 |
GOSSETT, LYNN S.;SHIH, CHUAN |
| 分类号 |
A61K31/505;A61P35/00;A61P43/00;C07D239/42;C07D239/48;C07D409/12;(IPC1-7):A61K31/505;C07D401/12 |
主分类号 |
A61K31/505 |
| 代理机构 |
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