| 摘要 |
PCT No. PCT/US91/06174 Sec. 371 Date Mar. 3, 1993 Sec. 102(e) Date Mar. 3, 1993 PCT Filed Sep. 4, 1991.This invention encompasses compounds of the formula: <IMAGE> and pharmaceutically acceptable non-toxic salts thereof wherein: n is 0, 1, or 2, X is <IMAGE> and R1, R2, R3, W and Y are variables These compounds are highly selective agonists, antagonists or inverse agonists for GABAa brain receptors or prodrugs thereof and are useful in the diagnosis and treatment of anxiety, sleep, and seizure disorders, overdose with benzodiazepine type drugs, and enhancement of alertness.
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