发明名称 |
4-Phenyl-3-substituted 1,4-dihydropyridine esters with cerebral activity. |
摘要 |
4-Phenyl 3-substituted 1,4-dihydropyridine esters are prepared by reacting benzaldehydes with keto esters and enamines, where appropriate with isolation of ylidene intermediates, or by esterification of corresponding dihydropyridinecarboxylic acids with alcohols. The 4-phenyl 3-substituted 1,4-dihydropyridine esters can be used as active ingredients in pharmaceuticals for the treatment of the central nervous system, in particular as cerebral therapeutic agents. |
申请公布号 |
EP0657431(A1) |
申请公布日期 |
1995.06.14 |
申请号 |
EP19940118672 |
申请日期 |
1994.11.28 |
申请人 |
BAYER AG |
发明人 |
MEIER, HEINRICH DR.;HARTWIG, WOLFGANG DR.;JUNGE, BODO DR.;SCHOHE-LOOP, RUDOLF DR.;GAO, ZHAN DR.;SCHMIDT, BERNARD DR.;DE JONGE, MAARTEN DR.;SCHUURMAN, TEUNIS DR. |
分类号 |
A61K31/4427;A61K31/455;A61P9/08;A61P25/24;A61P25/26;A61P25/28;C07D211/90;C07D401/12 |
主分类号 |
A61K31/4427 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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