发明名称 4-Phenyl-3-substituted 1,4-dihydropyridine esters with cerebral activity.
摘要 4-Phenyl 3-substituted 1,4-dihydropyridine esters are prepared by reacting benzaldehydes with keto esters and enamines, where appropriate with isolation of ylidene intermediates, or by esterification of corresponding dihydropyridinecarboxylic acids with alcohols. The 4-phenyl 3-substituted 1,4-dihydropyridine esters can be used as active ingredients in pharmaceuticals for the treatment of the central nervous system, in particular as cerebral therapeutic agents.
申请公布号 EP0657431(A1) 申请公布日期 1995.06.14
申请号 EP19940118672 申请日期 1994.11.28
申请人 BAYER AG 发明人 MEIER, HEINRICH DR.;HARTWIG, WOLFGANG DR.;JUNGE, BODO DR.;SCHOHE-LOOP, RUDOLF DR.;GAO, ZHAN DR.;SCHMIDT, BERNARD DR.;DE JONGE, MAARTEN DR.;SCHUURMAN, TEUNIS DR.
分类号 A61K31/4427;A61K31/455;A61P9/08;A61P25/24;A61P25/26;A61P25/28;C07D211/90;C07D401/12 主分类号 A61K31/4427
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