| 发明名称 |
1,2-dihydro-2-oxo-pyridines |
| 摘要 |
1-Biophenylylmethyl-2-oxo-3-aminomethyl-1,2-dihydropyridine derivs. of formula (I) and their salts are new: R1 = H; A; 2-6C alkenyl; or 2-6C alkynyl; R2 = -SO2NH-COOR5; -SO2NH-COR5; etc.;R3 = H; A;etc.;R4 = A-CO-, Ar'-CO-; Ar'-CmH2m-CO-;etc.;R5 = H; 1-6C alkyl opt. contg. O or S in place of 1 CH2 or opt. contg. a C-C double bond and opt. substd. by OH,etc.; A = 1-6C alkyl;Ar' = phenyl opt. mono- or di-substd.,etc.; m= 1-3. |
| 申请公布号 |
ZA9408311(B) |
申请公布日期 |
1995.06.14 |
| 申请号 |
ZA19940008311 |
申请日期 |
1994.10.21 |
| 申请人 |
MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG |
发明人 |
MATHIAS OSSWALD;DIETER DORSCH;NORBERT BEIER;INGEBORG LUES;WERNER MEDERSKI;PIERRE SCHELLING;KLAUS-OTTO MINCK |
| 分类号 |
A61K31/44;A61K31/4427;A61P9/00;A61P9/12;A61P27/02;A61P43/00;C07D213/64;C07D401/10;C07D413/10;C07D417/10;C07D419/10 |
主分类号 |
A61K31/44 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
