| 发明名称 |
Method for making intermediates useful in synthesis of retroviral protease inhibitors |
| 摘要 |
A synthesis is described for intermediates which are readily amenable to the large scale preparation of hydroxyethylurea-based chiral HIV protease inhibitors. The method includes forming a cyanohydrin from a chiral alpha amino aldehyde. |
| 申请公布号 |
AU1083395(A) |
申请公布日期 |
1995.06.13 |
| 申请号 |
AU19950010833 |
申请日期 |
1994.10.31 |
| 申请人 |
G.D. SEARLE & CO. |
发明人 |
JOHN S NG;CLAIRE A PRZYBYLA;RICHARD A. MUELLER;MICHAEL L VASQUEZ;DANIEL P GETMAN;JOHN J FRESKOS;GARY A DECRESCENZO;DEBORAH E BERTENSHAW;ROBERT M HEINTZ;SUHONG ZHANG;CHIN LIU;SCOTT A LANEMAN |
| 分类号 |
C07C213/00;C07C213/02;C07C213/08;C07C215/28;C07C221/00;C07C223/02;C07C253/30;C07C255/26;C07C269/04;C07C271/16;C07C271/18;C07C271/20;C07C273/18;C07C275/24;C07C309/73;C07D303/36;C07F7/18 |
主分类号 |
C07C213/00 |
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