| 发明名称 |
Process for the preparation of a stable factor VIII |
| 摘要 |
A process for the preparation of a pasteurized factor VIII concentrate with high specific activity and stability is described, which comprises adsorbing impurities from the solution containing the factor VIII by at least two-fold adsorption with Al(OH)3, an anion exchanger or Ca3(PO4)2, preferably with two different adsorbents from this group.
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| 申请公布号 |
US5424401(A) |
申请公布日期 |
1995.06.13 |
| 申请号 |
US19930166156 |
申请日期 |
1993.12.14 |
| 申请人 |
BEHRINGWERKE AKTIENGESESCHAFT |
发明人 |
HEIMBURGER, NORBERT;WELLNER, KLAUS;WENZ, KARL-HEINZ;KUMPE, GERHARDT |
| 分类号 |
A61K38/43;A61K35/16;C07K1/00;C07K1/16;C07K1/18;C07K14/435;C07K14/745;C07K14/755;(IPC1-7):C07K1/18 |
主分类号 |
A61K38/43 |
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