摘要 |
<p>The present invention provides a bacterium which contains a DNA coding sequence for a mosquitocidal toxin encoded by the B.sphaericus mtx gene or a modified mosquitocidal form thereof and which is capable of expressing the said toxin or modified mosquitocidal form thereof, said bacterium substantially lacking extracellular or intracellular proteases capable of degrading the said toxin or modified mosquitocidal form thereof. Such a bacterium may, for example, contain the complete mtx gene as present in B.sphaericus SSII-1 and may be obtained by appropriate transformation of a B.sphaericus strain of DNA homology group III or IV.</p> |