METHODS OF PROMOTING THE SURVIVAL AND DIFFERENTIATION OF SUBCLASSES OF CHOLINERGIC AND SEROTONERGIC NEURONS USING FIBROBLAST GROWTH FACTOR-5
摘要
The present invention relates to methods of promoting the survival and differentiation of subclasses of cholinergic and serotonergic neurons using fibroblast growth factor-5 (FGF-5). FGF-5 promotes the differentiation of cholinergic septal neurons as well as serotonergic neurons of the raphe nucleus.
申请公布号
WO9515176(A1)
申请公布日期
1995.06.08
申请号
WO1994EP03951
申请日期
1994.11.29
申请人
MAX-PLANCK-GESELLSCHAFT ZUR FOERDERUNG DER WISSENSC
发明人
LINDHOLM, DAN, B., W.;HARTIKKA, JUKKA, A.;BERZAGHI, MARIA, D.;CASTREN, EERO;TZIMAGIORGIS, GEORGIOS;HUGHES, RICHARD, A.;THOENEN, HANS