摘要 |
<p>Novel macrolide compounds (semisynthetic analogs of asomycin and FK-506) of formula (II) and phamaceutically acceptable salts, esters, amides and prodrugs thereof, wherein X is a substituent selected from among radicals having the subformulae (IIa), (IIe), (IIj) and (IIk) and other heretocyclic radicals, as well as pharmaceutical compositions and methods of immunomodulatory treatment utilizing same.</p> |