REVERSE DOT BLOT HYBRIDIZATION USING TANDEM HEAD-TO-TAIL MONOMERS CONTAINING PROBES SYNTHESIZED BY STAGGERED COMPLEMENTARY PRIMERS.

摘要

A method of detecting nucleic acid sequences in which polymers of selected oligonucleotide probes which are complementary to a region in a nucleic acid sequence that is to be detected are bound to a substrate. The polymers bound to the substrate contain multiple randomly repeated copies of a specific oligonucleotide probe and may be synthesized using enzymatic amplification techniques.