发明名称 |
Transdermal administration of amines with minimal irritation and high transdermal flux rate |
摘要 |
An effective amount of a skin irritating physiologically active amine can be transdermally or topically administered in a minimally or nonirritating composition that maintains a suitably high transdermal flux rate, by providing the amine as a minimally or nonirritating salt of a stoichiometric molar excess of a fatty acid of from 8 to 20 or 22 carbon atoms, in a nonpolar, nonvolatile solvent.
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申请公布号 |
US5422118(A) |
申请公布日期 |
1995.06.06 |
申请号 |
US19920948232 |
申请日期 |
1992.09.21 |
申请人 |
PURE PAC, INC. |
发明人 |
BROWN, LARRY R.;CLINE, JOHN F.;DAVIDSON, DECEASED, JAMES |
分类号 |
A61K9/00;A61K9/70;A61K47/12;A61K47/14;(IPC1-7):A61F13/00;A61K9/08;A61K31/13 |
主分类号 |
A61K9/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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