| 摘要 |
This invention relates to new isoxazoline compounds which are selective inhibitors of phosphodiesterase type IV (PDEIV). The new isoxazoline compounds are useful in inhibiting PDEIV and in the treatment of AIDS, asthma, arthritis, bronchitis, chronic obstructive pulmonary disease, psoriasis, allergic rhinitis, dermatitis, shock, atopic dermatitis, rheumatoid arthritis and osteoarthritis. This invention also relates to pharmaceutical compositions useful therefor.
|
