发明名称 NOVEL 9-HYDROXY-PYRIDO[1,2-A]PYRIMIDIN-4-ONE ETHER DERIVATIVES
摘要 The present invention is concerned with novel compounds having formula (I), the pharmaceutically acceptable acid addition salts thereof and the stereochemically isomeric forms thereof, wherein Alk represents C14alkanediyl; D is a bicyclic heterocycle of formula (a) or (b) wherein each R1 independently is C2-6alkenyl; C2-6alkynyl; C3-6cycloalkyl optionally substituted with C1-4alkyl; C1-19alkyl optionally substituted with C36cycloalkyl, halo, C1-6alkyloxy or cyano; and each R2 independently is hydrogen or C1-4alkyl. Novel compounds; compositions; processes for preparing novel compounds and intermediates are described.
申请公布号 CA2175372(A1) 申请公布日期 1995.06.01
申请号 CA19942175372 申请日期 1994.11.16
申请人 JANSSEN PHARMACEUTICA N.V. 发明人 VANDENBERK, JAN;KENNIS, LUDO EDMOND JOSEPHINE
分类号 A61K31/505;A61K31/519;A61P1/00;A61P25/04;A61P25/18;A61P25/20;A61P25/24;A61P25/26;A61P43/00;C07D471/04;(IPC1-7):C07D471/04 主分类号 A61K31/505
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