摘要 |
<p>Antipsychotic compounds having the formula <IMAGE> (I) wherein Z is H or Cl; Y is O or S; n is 1-4; separately, X is H or (C1-C2)alkyl and L is R(CH2)mCO, m is 0 or 1-3, R is (C1-C6)alkyl, (C3-C7)cycloalkyl, phenyl, naphthyl, furyl, benzofuranyl, thienyl, benzothienyl, pyrrolyl, indolyl, isoindolyl or one of said groups substituted on aromatic or heteroaromatic ring with fluoro, chloro, (C1-C2)alkyl or (C1-C2)alkoxy; or together L and X, in combination with the nitrogen to which they are attached, form certain cyclic imides, 4-substituted piperidines or a cyclic sulfonamide.</p> |