发明名称 NEUROLEPTIC PERHYDRO-1H-PYRIDO 1,2-a]PYRAZINES.
摘要 <p>Antipsychotic compounds having the formula <IMAGE> (I) wherein Z is H or Cl; Y is O or S; n is 1-4; separately, X is H or (C1-C2)alkyl and L is R(CH2)mCO, m is 0 or 1-3, R is (C1-C6)alkyl, (C3-C7)cycloalkyl, phenyl, naphthyl, furyl, benzofuranyl, thienyl, benzothienyl, pyrrolyl, indolyl, isoindolyl or one of said groups substituted on aromatic or heteroaromatic ring with fluoro, chloro, (C1-C2)alkyl or (C1-C2)alkoxy; or together L and X, in combination with the nitrogen to which they are attached, form certain cyclic imides, 4-substituted piperidines or a cyclic sulfonamide.</p>
申请公布号 EP0573467(B1) 申请公布日期 1995.05.31
申请号 EP19920904861 申请日期 1991.11.18
申请人 PFIZER INC. 发明人 BRIGHT, GENE, MICHAEL;DESAI, KISHOR, AMRATLAL;SEEGER, THOMAS, FRANCIS
分类号 A61K31/495;A61K31/4985;A61P25/18;C07D;C07D211/60;C07D211/62;C07D401/14;C07D471/04;C07D519/00;(IPC1-7):C07D471/04 主分类号 A61K31/495
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