发明名称 |
COMPOUNDS CONTAINING CONDENSED BIOCYCLIC RING AND A METHOD FOR THEIR PREPARATION |
摘要 |
<p>Compounds of the formula <CHEM> wherein X is O or S-(O)t; n is one or two; m is zero or one; Y is CH2, O, or S-(O)t provided that Y is O or S-(O)t only when m is one; and A is <CHEM> are dual inhibitors of NEP and ACE. Compounds wherein A is <CHEM> are selective ACE inhibitors. Also disclosed are methods of preparation and intermediates.</p> |
申请公布号 |
BG98854(A) |
申请公布日期 |
1995.05.31 |
申请号 |
BG19940098854D |
申请日期 |
1994.06.14 |
申请人 |
BRISTOL-MYERS SQUIBB COMPANY |
发明人 |
ROBL, JEFFREY A.;KRONENTHAL, DAVID R.;GODFREY, JOLLIE D. |
分类号 |
A61K31/535;A61K31/5365;A61K31/5383;A61K31/54;A61K31/542;A61K31/55;A61K31/553;A61K31/554;A61K38/00;A61P9/04;A61P9/12;A61P43/00;C07C315/02;C07C317/50;C07C319/14;C07C319/20;C07C323/59;C07C327/34;C07D;C07D498/04;C07D513/04;C07K5/078;(IPC1-7):A61K31/535 |
主分类号 |
A61K31/535 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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