发明名称 |
Tri- and tetra-substituted-oxetanes and -tetrahydrofurans and intermediates thereof. |
摘要 |
<p>This invention relates to tri- and tetra-substituted-oxetanes of the formula, <CHEM> e.g. (+/-)-cis- and (+/-)-trans-2-[(4-(4-isopropylpiperazin-1-yl)phenoxy)methyl]-4-(2,4-di halop henyl)-4-[1H-1,2,4-triazol-1-yl)methyl]oxetane and tri- and tetra- substituted-tetrahydrofurans, e.g. (+/-)-cis- and (+/-)-trans-1-[4-[[2-(2,4-dihalophenyl)tetrahydro-2-[(1H-azol-1-yl)m ethyl]-5-furanyl]methoxy]phenyl]-4-yl-1-substituted piperazine-3-one and related derivatives which exhibit antifungal and antiallergy activities, pharmaceutical composition thereof, methods of their use in treating or preventing susceptible fungal infections and allergic reactions in a host including warm-blooded animals such as humans.</p> |
申请公布号 |
GR3015217(T3) |
申请公布日期 |
1995.05.31 |
申请号 |
GR19950400421T |
申请日期 |
1995.02.28 |
申请人 |
SCHERING CORPORATION |
发明人 |
SAKSENA, ANIL K.;GANGULY, ASHIT K.;GIRIJAVALLABHAN, VIYYOOR M.;RANE, DINANATH F. |
分类号 |
C07D473/08;A61K31/41;A61K31/415;A61K31/425;A61K31/44;A61K31/443;A61K31/4433;A61K31/495;A61K31/52;A61K31/522;A61P29/00;A61P31/00;A61P37/08;C07D405/06;C07D405/14;C07D409/14;C07D417/14;C07D473/10;C07D493/08;C07D521/00;(IPC1-7):C07D405/06;A61K31/38 |
主分类号 |
C07D473/08 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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