发明名称 |
Methods of treating circadian rhythm disorders |
摘要 |
A method for treating circadian rhythm disorders is described. The method involves the administration of melatonin from about 6 hours to about 19 hours prior to when the normal sleep phase should begin, depending on whether a phase advance shift in circadian rhythms or a phase delay shift is desired. This is typically from about 4 hours to about 17 hours prior to the time of endogenous melatonin onset.
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申请公布号 |
US5420152(A) |
申请公布日期 |
1995.05.30 |
申请号 |
US19930077426 |
申请日期 |
1993.06.15 |
申请人 |
STATE OF OREGON, ACTING BY AND THROUGH THE OREGON STATE BOARD OF HIGHER EDUCATION ON BEHALF OF THE OREGON HEALTH SCIENCES UNIVERSITY, A NON-PROFIT ORGANIZATION |
发明人 |
LEWY, ALFRED J.;SACK, ROBERT L. |
分类号 |
A61K9/22;A61K9/52;A61K31/40;A61K31/4045;A61K45/06;(IPC1-7):A61K31/40 |
主分类号 |
A61K9/22 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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